Proteomics solutions you can trust
Matrix Science develops software solutions for mass spectrometry proteomics. Mascot is a great choice for researchers, core labs, industry and educators.
Many third-party systems integrate directly with Mascot: Thermo Proteome Discoverer™, Bruker BioPharma Compass, Progenesis QI, Waters PLGS, Genedata Expressionist and Proteome Software Scaffold.
Blog
February 14, 2025
Mascot Distiller can now use machine learning with LFQ, TMT and other quantitation methods, thanks to API changes made in the recent Mascot Server 3.1 release. Machine learning typically increases [...]
News
February 10, 2025
Mascot Distiller 2.8.5.1 is a minor patch release. This release fixes a single bug which is required to enable machine learning score refinement with Mascot Server 3.1. The update is [...]
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Protein identification
Mascot Server is the trusted reference standard for protein identification by mass spectrometry for 25 years. Mascot is designed for high throughput, and has no limits on the number of users, the size of the searches or the size of sequence databases. It continues to be cited by over 2000 publications every year.
Mascot Distiller provides additional tools for protein identification, including manual and automatic de novo sequencing.
Protein quantitation
Mascot Server includes native support for TMT/iTRAQ quantitation.
Mascot Distiller is a vendor independent Windows workstation application for quantifying proteins and peptides from a Mascot database search. Use any MS1 quantition, such as: SILAC, 18O, metabolic labelling and label-free methods (LFQ). Process raw files from Agilent, Bruker, SCIEX, Shimadzu, Thermo and Waters.
Batch automation
Mascot Daemon is a batch automation utility, bundled with Mascot Server. In combination with Mascot Distiller, every step of a quantitation experiment can be fully automated.
Mascot Parser provides an API (Application Programmer Interface) to Mascot Server result files and Mascot Distiller project files, suitable for implementing your own system integrations and pipelining.