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Archive

Date	Topics
December 2024	• Predicted fragment intensities with Mascot Server 3.0 • Self-ligating surface receptor and CD8+ T-cells • Saving search results as HTML	English Japanese Chinese
November 2024	• Predicted retention times in Mascot Server 3.0 • N-terminal methylation of Physcomitrella organellar proteins • Mascot Server 3.0 compatibility	English Japanese Chinese
October 2024	• Mascot Server 3.0 is released • Thermal proteome profiling and affinity ultrafiltration for analysing natural products • Mascot at HUPO 2024	English Japanese Chinese
September 2024	• Machine learning in Mascot Server 3.0 • Untargeted identification of viruses • Preorder Mascot 3.0 now	English Japanese Chinese
August 2024	• 30 years of Sequence Tags • Proteomics of peanut allergens • Error tolerant sequence tag example	English Japanese Chinese
July 2024	• Mascot workflow for LC-MS/MS • Adaptive epigenetic changes in histone variants • Free temporary licence for migration	English Japanese Chinese
June 2024	• Breakfast meeting summary • Mascot at ASMS 2024	English Japanese Chinese
May 2024	• ASMS User Meeting • Optimizing sample preparation with an artificial neural network • Free Mascot service	English Japanese Chinese
April 2024	• ASMS User Meeting • Wind effect in plant protein expression • New distributor in Europe	English Japanese Chinese
March 2024	• Guest user settings • Impact of software on fast photochemical oxidation of protein (FPOP) analysis • Mascot for your research lab	English Japanese Chinese
February 2024	• Unsuspected mods with DIA • Spatial heterogeneity of uterine cancer tumors • Deleting obsolete predefined definitions	English Japanese Chinese
January 2024	• Narrow window DIA • Ubiquitylation and DNA damage response • Windows Server 2019	English Japanese Chinese
December 2023	• ABRF Crosslinking Study • N-terminal acetylation shields proteins from degradation • Internal fragments with HCD	English Japanese Chinese
November 2023	• Chimeric spectra • Characterizing Shewanella integral membrane complex • Mascot Distiller 2.8.5	English Japanese Chinese
October 2023	• Distiller’s 20th anniversary • LAP-MALDI MS for detection of bovine tuberculosis • Automated Distiller reports	English Japanese Chinese
September 2023	• Software version numbers • Mapping the human chondroitin sulfate glycoproteome • Mascot Server 2.8.3	English Chinese Japanese
August 2023	• Optimise your chunk size • Sequencing isomeric proteoforms using cyclic ion mobility and ECD • Mascot Distiller 2.8.4	English Chinese Japanese
July 2023	• Creating DIA spectral libraries • Mass spectral analyses of Salmonella myovirus • Crosslinking with DSSO	English Chinese Japanese
June 2023	• User meeting slides • Mascot posters at ASMS • Updated training materials	English Chinese Japanese
May 2023	• Breakfast meeting at ASMS • High-throughput venomics • Mascot in the Cloud	English Chinese Japanese
April 2023	• Breakfast meeting at ASMS • Bioinertization of nanoLC/MS/MS systems for phosphoproteomics • 25 years of Matrix Science	English Chinese Japanese
March 2023	• Crosslinked peak picking • Targeted protein dephosphorylation • Batch scripting with Distiller	English Chinese Japanese
February 2023	• Paleoproteomics • Biomarkers in the exosome of endometrial cancer serum • Staying up to date	English Chinese Japanese
January 2023	• Complementary reporter ions • Growing ryegrass on Martian regolith simulant • Free disk space	English Chinese Japanese
December 2022	• Distiller quant reports • Tubulin glutamylation and glycylation • TMTpro quant methods	English Chinese Japanese
November 2022	• Trusting your search engine • Temporal phosphoproteomics of EV-A71-infected cells • Virtualisation	English Chinese Japanese
October 2022	• Fractionated LFQ • PMF of preserved collagen in archaeological fish bones • System limits on Linux	English Chinese Japanese
September 2022	• mzIdentML 1.2 • Biomarkers of residual malaria parasites • Mascot Server 2.8.2	English Chinese Japanese
August 2022	• SARS-CoV-2 spike protein disulfide bonds • Protein products of non-coding transcripts • Disaster recovery	English Chinese Japanese
July 2022	• Single-cell spectra • VAMS-Trypsin immobilization for instant proteolysis • New pricing for updating old licences	English Chinese Japanese
June 2022	• ASMS presentations • Identification of Protein Isoforms using RNA-seq reads • False Discovery Rates	English Chinese Japanese
May 2022	• ASMS User Meeting • Peak picking with Distiller • Androgen receptor interactions • Glycans in Unimod	English Chinese Japanese
April 2022	• ASMS User Meeting • NCBI nr tips • Filter-aided sample preparation • Mascot Server patch	English Chinese Japanese
March 2022	• Linux cluster security • Glycation in milk • EST Fasta files	English Chinese Japanese
February 2022	• FTP retirement • Histone code of the malaria parasite • Mascot Distiller update	English Chinese Japanese
January 2022	• Hardware for Mascot Distiller • Serological testing for SARS-CoV-2 • Making Protein Family Summary the default report	English Chinese Japanese
December 2021	• Endogenous peptides • Solid phase extraction • Mascot Daemon housekeeping	English Chinese Japanese
November 2021	• ASMS 2021 presentations • 3D bioprinted tumor models	English Chinese Japanese
October 2021	• Disk bottlenecks • N-terminally ubiquitinated proteins • Local vs. public modifications	English Chinese Japanese
September 2021	• Error tolerant search statistics • Anti-bacterial peptides • Exporting ion mobility values	English Chinese Japanese
August 2021	• Ion mobility filtering • Proteomics of Primary Uveal Melanoma • Mascot Server 2.8 release	English Chinese Japanese
July 2021	• LFQ with Mascot Distiller 2.8 • Mapping proximity associations • Retention time in Percolator	English Chinese Japanese
June 2021	• Counterfeit cashmere • Protein carriers • Mascot Server 2.8	English Chinese Japanese
May 2021	• Unipept for taxonomy assignment • Extracellular matrix proteome • Mascot Distiller 2.8	English Chinese Japanese
April 2021	• Updated NIST Human spectral libraries • Histone methylation profiling • Standard enzyme definitions	English Chinese Japanese
March 2021	• Sizing a Mascot Server license • Collagen in Ancient Bone • NCBI nr alternatives	English Chinese Japanese
February 2021	• Single Sign-On • Zirconium-IMAC • Variable modification tuning	English Chinese Japanese
January 2021	• de novo Competition Results • Automated plasma proteome preparation • Cross-link modification	English Chinese Japanese
December 2020	• de novo Competition • Database management • ADP-ribosylated peptidesk • Spectral quality tutorial	English Chinese Japanese
November 2020	• Crosslinked peptide ID • Enriching N-terminal peptides • Client error message quirk	English Chinese Japanese
October 2020	• Quantitation charts and plots • Sialylation in rat nerve terminals • Custom and predefined database configurations	English Chinese Japanese
September 2020	• Variable modifications • Aberrant N-glycosylation • Support and update reminder	English Chinese Japanese
August 2020	• Summarizing quantitation data • Host cell proteins in biopharmaceuticals • Database Manager error message	English Chinese Japanese
July 2020	• Human Proteome Project Guidelines • Cysteine quantitation • Creating new crosslinking methods	English Chinese Japanese
June 2020	• ASMS Reboot Presentations • Quantitation p-values	English Chinese Japanese
May 2020	• Remote working • Shotgun proteomics of SARS-CoV-2 • Finding help topics	English Chinese Japanese
April 2020	• Protein FDR • N-term Arg and Lys enzyme • New databases on public server	English Chinese Japanese
March 2020	• Disaster Recovery • In-line sample preparation • Spectral library creation	English Chinese Japanese
February 2020	• Search reproducibility • Ion mobility separation of proteoforms • Modifications in spectral libraries	English Chinese Japanese
January 2020	• Mascot Server 2.7 • mAb sequence validation • Uniprot proteomes	English Chinese Japanese
December 2019	• Protein scores • Persulfidation • Access database engine	English Chinese Japanese
November 2019	• Diethylation • Ionic liquid-based sample preparation • IIS configuration	English Chinese Japanese
October 2019	• Shared peptides • Palmitoylation And Nitrosylation Interplay Monitoring • Fixed and variable modifications	English Chinese Japanese
September 2019	• Benchmarking protein inference • Photosynthetic apparatus of Pinaceae • Controlling search priorities	English Chinese Japanese
August 2019	• Peptide-spectrum match statistics • Epitope mapping by direct nano-electrospray MS • Windows versus Linux version of Mascot	English Chinese Japanese
July 2019	• Proteome Discoverer workflows • Summed intensities improve iTRAQ accuracy • Neutral loss configuration	English Chinese Japanese
June 2019	• Metaproteomics with Mascot • Middle-Down searching • Exclusive mods, combination mods, metabolic labelling	English Chinese Japanese
May 2019	• ASMS User Meetings 2019 • Daemon automation • Analysis of C Terminome • Distiller quantitation speed-up	English Chinese Japanese
April 2019	• ASMS User Meetings 2019 • X!Hunter spectral libraries • Identification of PEG-based detergents • Combining Mascot Server licences	English Chinese Japanese
March 2019	• Proteomic Forum 2019 • O-glycosylated peptides • Adsorption-based sample preparation • Capturing error messages	English Chinese Japanese
February 2019	• Use spectral libraries today • High-resolution spatial proteomics • Enzyme mixtures	English Chinese Japanese
January 2019	• 1 Da modifications • Unexpected modifications • Using Report Builder	English Chinese Japanese
December 2018	• Quantitation statistics • Single Amino Acid Variant discovery • De-charging a peak list	English Chinese Japanese
November 2018	• Mascot Server cluster mode • Ion suppression in phosphoproteomics • Rebuilding the search log	English Chinese Japanese
October 2018	• Common mistakes • Deep dive on human CSF • Troubleshooting corrupt XML	English Chinese Japanese
September 2018	• Search parameter optimization • Identifying proteins in ancient paintings • NCBIprot maximum sequence length	English Chinese Japanese
August 2018	• Free consultations at HUPO • Mascot Distiller speed • Fibronectin Proteolysis • Filtering out short peptides	English Chinese Japanese
July 2018	• HUPO consultation sessions • Quantitation of cysteine oxidation • Catechol Estrogens • Editing the Mascot Daemon task database	English Chinese Japanese
June 2018	• Genome database updates • Determination of site-specific phosphorylation ratios • Troubleshooting Mascot Daemon	English Chinese Japanese
May 2018	• ASMS User Meetings • HTTPS Issues • Mining the human tissue proteome for protein citrullination • Mascot Server 2.6.2	English Chinese Japanese
April 2018	• 20-20 Special Offer • ASMS Workshops • MS3 Reporter Ions • Tip-based identification of protease substrates • Mascot Distiller 2.7	English Chinese Japanese
March 2018	• 25 years of protein ID • Glycopeptide identification • PC hardware specification	English Chinese Japanese
February 2018	• Dark matter challenge results round-up • Biomarkers for Alzheimer’s • Model Distiller project	English Chinese Japanese
January 2018	• Shared task database • Peptide biomarkers for ovarian cancer • UniProt reference proteome	English Chinese Japanese
December 2017	• Alkylation issues • Detergents for Membrane Protein Complexes • Controlling running searches	English Chinese Japanese
November 2017	• Contaminants spectral library • Non-canonical phosphorylation • Excluding modifications from error tolerant search	English Chinese Japanese
October 2017	• Trypsin autolysis • Kinase activity ranking • Disabling cache files	English Chinese Japanese
September 2017	• Which ions series? • SLIM labelling • Modifying the taxonomy tree	English Chinese Japanese
August 2017	• Mascot security • Protein N-term characterization • Quantitation of extreme ratios	English Chinese Japanese
July 2017	• Dark matter challenge • Alkylation side-effects • Anti-virus advice	English Chinese Japanese
June 2017	• Exporting search results • Detection of methicillin-resistant S. aureus • Housekeeping automation	English Chinese Japanese
May 2017	• ASMS breakfast meetings • Peak lists • Giant Buddhas • Reporting combined results	English Chinese Japanese
April 2017	• ASMS breakfast meetings • Protein FDR • Protein carbonylation • Adding a new element	English Chinese Japanese
March 2017	• Proteomics repositories • Trace-level residual proteins in human Ig • Processing options files in Mascot Distiller	English Chinese Japanese
February 2017	• Chimeric spectra • Yeast small subunit processome • Initiator Met	English Chinese Japanese
January 2017	• Retention Time in Mascot • The Protein Co-Migration Database • Why summary reports no longer show non-significant matches	English Chinese Japanese
December 2016	• Spectral library searching • The epichaperome • Mascot Daemon 2.6	English Chinese Japanese
November 2016	• Hardware for Mascot Server • Proteasome-generated spliced peptides • Very long sequences	English Chinese Japanese
October 2016	• Multiple fragmentation methods • Phosphoproteomics of Flu • Ambiguous residues	English Chinese Japanese
September 2016	• High FDRs for methylated peptides • Protein primary structure of the Vaccinia virion • NCBI have dropped gi number identifiers	English Chinese Japanese
August 2016	• HUPO 2016 • mzTab export • HLA-DR bound peptides • Negative ions	English Chinese Japanese
July 2016	• Unlabelled peaks • Bacterial Interactomes • Peptide charge state	English Chinese Japanese
June 2016	• Mascot Distiller 2.6 • Circadian clock proteins • Mysterious crashes	English Chinese Japanese
May 2016	• ASMS breakfast meetings • Selenocysteine and U • Tetracycline-inhibited ribosome profiling • The database *.stats file	English Chinese Japanese
April 2016	• ASMS breakfast meetings • ETD analysis of Histone Proteoforms • Web server timeout	English Chinese Japanese
March 2016	• Search only for peptides we care about • Cryo-slicing Blue Native-MS • YouTube video	English Chinese Japanese
February 2016	• Quality assurance • Histone PTMs • Command line search	English Chinese Japanese
January 2016	• Listing confidently identified proteins • California sea lion CSF • Introductory tutorials	English Chinese Japanese
December 2015	• Baker Street • Methionine Sulfoxide Dynamics • Distiller project viewer	English Chinese Japanese
November 2015	• Mass-tolerant search • S-glutathionylation • CID+ETD Instrument	English Chinese Japanese
October 2015	• De novo sequencing • Giant virus from permafrost • Intensity values for components	English Chinese Japanese
September 2015	• Mascot Distiller • Microbial antigen typing • Customizing modifications	English Chinese Japanese
August 2015	• Search with ESTs • Identification of Regulatory and Cargo Proteins • Mascot Security	English Chinese Japanese
July 2015	• How do I do that? • Enrichment of Vesicular Glycoproteins • Webcast training course updated	English Chinese Japanese
June 2015	• Mascot Server in "The Cloud" • Online Peptide Fractionation Using an LC-chip • Mascot tip – Auto-export in Mascot Daemon	English Chinese Japanese
May 2015	• ASMS User Meeting • Site analysis • Global Analysis of Myocardial Peptides • Mascot tip – Glycopeptide analysis	English Chinese Japanese
April 2015	• ASMS User Meeting • Mascot on a virtual machine • Phospho-iTRAQ: Assessing Isobaric Labels for the Large-Scale Study Of Phosphopeptide Stoichiometry • Mascot tip – Migrating to new hardware	English Chinese Japanese
March 2015	• DIA-Umpire enables database searching of DIA data • The first step of peptide selection in antigen presentation by MHC class I molecules • Mascot tip – Peak list re-centroiding	English Chinese Japanese
February 2015	• Quantify then identify or identify then quantify? • Deciphering Preferential Interactions within Supramolecular Protein Complexes: the Proteasome Case • Large Scale Proteomics symposium at Proteomic Forum 2015 • Mascot tip – Mascot Daemon data import filters	English Chinese Japanese
January 2015	• The true benefit of high mass accuracy • Rapid Identification and Quantitative Validation of a Caffeine-Degrading Pathway in Pseudomonas sp. CES • Large Scale Proteomics symposium at Proteomic Forum 2015	English Chinese Japanese
December 2014	• Why can’t I search with more than 9 variable modifications? • Targeting Synaptic Pathology with a Novel Affinity Mass Spectrometry Approach • New patch for Mascot Server 2.5	English Chinese Japanese
November 2014	• How long should my search take? • Tracking Cancer Drugs in Living Cells by Thermal Profiling of the Proteome • Mascot Server 2.5 now available	English Chinese Japanese

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