Mascot: The trusted reference standard for protein identification by mass spectrometry for 25 years

Exercise MSMS6

Topic

MS/MS search of some Electron Transfer Dissociation data

Requirements

User access to any Mascot server, including the Matrix Science public web site

Experimental

Data from BSA analysed on an Orbitrap using ETD. Cysteine residues reduced and alkylated with iodoacetic acid (+58). Can use precursor tolerance of 2 ppm and fragment tolerance of 0.1 Da. Trypsin with 1 missed cleavage.

Data

Right-click this link: MSMS6.mgf, and choose Save target as or Save link as

Questions

  1. Did the peak detection ever fail to pick the 12C peak?
  2. What do you get if you search as CID?

 

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